The c.3274T> C mutation in the CFTR gene results in bronchiectasis and loss of lung function in a 44-year-old Peruvian woman: A very rare condition

CF is an autosomal recessive disease, requiring mutations to be present in both alleles the transmembrane conductance regulatory gene (CFTR). The c.3274T> C (p.Tyr1092His) mutation not registered “CFTR2 project” database, but it Human Gene Mutation Database. Neither are two DNAAF4 c.1177C> T (p.Leu393Phe) and DNAAF5 c.1195G> A (p.Glu399Lys) found "CFTR Project”, their clinical consequences currently uncertain. Here, we report case of a Peruvian woman presenting this mutation, bronchiectasis loss lung function provide review literature.